Author

Claire E. Tocheny

University of Massachusetts Chan Medical SchoolORCID 0000-0002-5791-7560Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Anastasia KhvorovaiD· 1 shared Arthur M. MercurioiD· 1 shared Ashley SummersiD· 1 shared Christi A. Silva· 1 shared Christopher D Dahlke· 1 shared Cornelia PetersoniD· 1 shared Dimas EcheverriaiD· 1 shared Hassan H. FakihiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Anastasia KhvorovaORCID

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1 paper

Recent·Most cited

Therapeutic delivery of albumin-binding siRNA targeting IRS2 to diverse cell types reduces mammary tumor growth

Claire E. Tocheny, Julianna E. Buchwald, Christopher D Dahlke, Hassan H. Fakih, Jennifer S. Morgan, Ashley Summers, Christi A. Silva, Samuel O. Jackson, Ji-Sun Lee, Michael-Anthony Card, Dimas Echeverria, Cornelia Peterson, Arthur M. Mercurio, Anastasia Khvorova, Leslie M. Shaw

This study delivers IRS2-targeting siRNAs to mammary tumors via albumin-binding dendrimers, reducing tumor growth by inhibiting Irs2 expression and altering tumor microenvironment features.

Molecular Therapy · Jan 29, 2026Peer-reviewedCancer Biology