Author

Samuel O. Jackson

University of Massachusetts Chan Medical School

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Anastasia KhvorovaiD· 2 shared Dimas EcheverriaiD· 2 shared Arthur M. MercurioiD· 1 shared Ashley SummersiD· 1 shared Batuhan YenilmeziD· 1 shared Brianna M. BramatoiD· 1 shared Chloe DiMarzio· 1 shared Christi A. Silva· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Anastasia KhvorovaORCID

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2 papers

Recent·Most cited

Therapeutic delivery of albumin-binding siRNA targeting IRS2 to diverse cell types reduces mammary tumor growth

Claire E. Tocheny, Julianna E. Buchwald, Christopher D Dahlke, Hassan H. Fakih, Jennifer S. Morgan, Ashley Summers, Christi A. Silva, Samuel O. Jackson, Ji-Sun Lee, Michael-Anthony Card, Dimas Echeverria, Cornelia Peterson, Arthur M. Mercurio, Anastasia Khvorova, Leslie M. Shaw

This study delivers IRS2-targeting siRNAs to mammary tumors via albumin-binding dendrimers, reducing tumor growth by inhibiting Irs2 expression and altering tumor microenvironment features.

Molecular Therapy · Jan 29, 2026Peer-reviewedCancer Biology

Dual targeting of hepatocyte DGAT2 and stellate cell FASN alleviates nonalcoholic steatohepatitis in mice.

Batuhan Yenilmez, Shauna M. Harney, Chloe DiMarzio, Mark Kelly, Kyounghee Min, Dimas Echeverria, Brianna M. Bramato, Samuel O. Jackson, Keith R. Reddig, Jason K. Kim, Anastasia Khvorova, Michael Czech

This study shows that targeting both DGAT2 in hepatocytes and FASN in stellate cells reduces NASH in mice more effectively than targeting either gene alone.

bioRxiv · Jul 5, 2023 · PreprintMolecular Biology