Alphée Michelot

The paper identifies Ldb17 as the on-switch for endocytic actin assembly in S. cerevisiae, revealing its complex regulation by Sla1 and evolutionary divergence from Dip1 in S. pombe.

This study reveals that MreB filaments in Bacillus subtilis renew their nucleotide state through intrafilament exchange without subunit turnover, linking filament stability to the surrounding nucleotide pool.

The paper investigates the role of RomRX and MglB in regulating cell polarity in Myxococcus xanthus, showing RomRX acts as an effector of MglAGTP and competes with MglB to modulate complex stability.

This study investigates how ATP and ADP binding affects MreB polymerization and membrane interaction in Geobacillus stearothermophilus, revealing distinct binding affinities and membrane fluidizing effects.

This study compares actin filament assembly and disassembly kinetics between two yeast species and mammalian actin, revealing faster aging in yeast actins due to the absence of histidine 73 methylation.

This study introduces in vitro assays to quantify actin-binding protein (ABP) activity in actin turnover and identifies conditions that maximize turnover efficiency.

This study develops a biophysical model of actin filament bundles to determine optimal conditions for mechanical power generation under external forces.