Biplab Dasgupta

Cardiomyocyte-intrinsic SLC25A1 regulates cardiac differentiation and mitochondrial function

This study shows that SLC25A1 in cardiomyocytes regulates differentiation, mitochondrial function, and cardiac development, linking mitochondrial citrate export to developmental gene programs.

Integrative Multi-Omics Analysis Identifies Nuclear Factor I as a Key Driver of Dysregulated Purine Metabolism in DIPG

This study identifies nuclear factor I (NFI) as a driver of dysregulated purine metabolism in DIPG, showing that targeting ATIC reduces tumor progression in mice.

Copb2 Is Essential For Embryogenesis And Hypomorphic Mutations Cause Human Microcephaly

The paper identifies COPB2 mutations as a cause of human microcephaly and shows that Copb2 is essential for embryogenesis and corticogenesis in mice.