Author

Janki M. Desai

University of CincinnatiORCID 0000-0002-8673-1327Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Abby GrieriD· 1 shared Ali TavassoliiD· 1 shared Angelo D’AlessandroiD· 1 shared Biplab DasguptaiD· 1 shared Cailing Yin· 1 shared Charles B. StevensoniD· 1 shared Claire Xin SuniD· 1 shared Ian MersichiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Abby GrierORCID

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1 paper

Recent·Most cited

Integrative Multi-Omics Analysis Identifies Nuclear Factor I as a Key Driver of Dysregulated Purine Metabolism in DIPG

Ian Mersich, Sunny Congrove, Matthew J. Horchar, Román Cáceres, Ranjithmenon Muraleedharan, Janki M. Desai, Pankaj B. Desai, Larry Sallans, Julie A. Reisz, Abby Grier, Matthew R. Hass, Omer Donmez, Cailing Yin, Matthew T. Weirauch, Leah Claire Kottyan, , Biplab Dasgupta

This study identifies nuclear factor I (NFI) as a driver of dysregulated purine metabolism in DIPG, showing that targeting ATIC reduces tumor progression in mice.

bioRxiv · May 21, 2025 · PreprintCancer Biology