Author

Abby Grier

University of Colorado AnschutzORCID 0000-0002-5199-8670Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:mouse· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Angelo D’AlessandroiD· 3 shared Julie A. ReisziD· 2 shared Aaron P. HavasiD· 1 shared Adarsh RajeshiD· 1 shared Alessandra SaccoiD· 1 shared Ali TavassoliiD· 1 shared Anagha Inguva ShethiD· 1 shared Andrew E. M. DavisiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCancer Biology

Angelo D’AlessandroORCID

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3 papers

Recent·Most cited

The STAT3-VDAC1 Axis Modulates Mitochondrial Function and Plays a Critical Role in the Survival of Acute Myeloid Leukemia Cells

Kellen B. Gil, Jamie L. Borg, Rosana Moreira Pereira, Anagha Inguva Sheth, Geovana Araujo, Jeremy Rahkola, William Showers, Abby Grier, Angelo D’Alessandro, Clayton A. Smith, Christine M. McMahon, Daniel Aaron Pollyea, Austin E. Gillen, Maria L. Amaya

Haematologica · Jun 19, 2025Peer-reviewedCancer Biology

Integrative Multi-Omics Analysis Identifies Nuclear Factor I as a Key Driver of Dysregulated Purine Metabolism in DIPG

Ian Mersich, Sunny Congrove, Matthew J. Horchar, Román Cáceres, Ranjithmenon Muraleedharan, Janki M. Desai, Pankaj B. Desai, Larry Sallans, Julie A. Reisz, Abby Grier, Matthew R. Hass, Omer Donmez, Cailing Yin, Matthew T. Weirauch, Leah Claire Kottyan, , Biplab Dasgupta

This study identifies nuclear factor I (NFI) as a driver of dysregulated purine metabolism in DIPG, showing that targeting ATIC reduces tumor progression in mice.

bioRxiv · May 21, 2025 · PreprintCancer Biology

Activated Interferon Signaling Suppresses Age-Dependent Liver Cancer

Aaron P. Havas, Kathryn Lande, Adarsh Rajesh, K. Garrett Evensen, Siva Karthik Varanasi, Linshan Shang, Elizabeth K. Schmidt, Jin Lee, Kenneth H. Kim, Marcos Garcia Teneche, Filipe Araujo Hoffmann, Michael LaPorte, Andrew E. M. Davis, Abby Grier, Julie A. Reisz, , Peter D. Adams

This study shows that aged livers have heightened interferon signaling that suppresses cancer but also has harmful effects, leading to a 'precarious balance' in tumor development.

bioRxiv · Jul 31, 2024 · PreprintCancer Biology