Jonathan Wickel

This study investigates functional connectivity changes in murine models of NMDAR antibody-associated pathology using rs-fMRI, finding impaired connectivity in hippocampal regions similar to human patients.

The paper demonstrates that patient-derived monoclonal GABAA receptor antibodies cause catatonia and seizures in rodents, providing a model for autoimmune encephalitis and supporting antibody depletion as a treatment.

This study identifies synaptic pathomechanisms of sepsis-associated encephalopathy and demonstrates that targeted rescue of synaptic plasticity can improve cognitive decline in a mouse model.