Author

Peter M. Fischer

University of NottinghamORCID 0000-0002-5866-9271Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Akeel Abo AlardiD· 1 shared Alan John WarreniD· 1 shared Alexandre FailleiD· 1 shared Alisa F. ZyryanovaiD· 1 shared Ana Crespillo-CasadoiD· 1 shared Christophe FromontiD· 1 shared David RoniD· 1 shared Felicity R. AlleniD· 1 shared

Activity by Year

2017-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Akeel Abo AlardORCID

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1 paper

Recent·Most cited

Binding of the integrated stress response inhibitor, ISRIB, reveals a regulatory site in the nucleotide exchange factor, eIF2B

Alisa F. Zyryanova, Félix Weis, Alexandre Faille, Akeel Abo Alard, Ana Crespillo-Casado, Heather P. Harding, Felicity R. Allen, Leopold Parts, Christophe Fromont, Peter M. Fischer, Alan John Warren, David Ron

The paper identifies an ISRIB-binding site in eIF2B using cryo-EM and CRISPR/Cas9, showing its role in regulating translation through an allosteric mechanism.

bioRxiv · Nov 25, 2017 · PreprintMolecular Biology