Author

Alisa F. Zyryanova

University of CambridgeORCID 0000-0002-9885-6012Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

David RoniD· 2 shared Heather P. HardingiD· 2 shared Akeel Abo AlardiD· 1 shared Alan John WarreniD· 1 shared Alexandre FailleiD· 1 shared Ana Crespillo-CasadoiD· 1 shared Anders GunnarssoniD· 1 shared Anthony D. KeefeiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

David RonORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedMay 6, 2026

A molecular stabiliser of an inhibitory eIF2B-eIF2(αP) complex activates the Integrated Stress Response

Fiona Shilliday, Miguel Gancedo-Rodrigo, Ginto George…·John E. Linley

The paper identifies a chemical inhibitor of eIF2B that activates the Integrated Stress Response by stabilizing an inhibitory complex with phosphorylated eIF2.

1 citation

experimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintNov 25, 2017

Binding of the integrated stress response inhibitor, ISRIB, reveals a regulatory site in the nucleotide exchange factor, eIF2B

Alisa F. Zyryanova, Félix Weis, Alexandre Faille…·David Ron

The paper identifies an ISRIB-binding site in eIF2B using cryo-EM and CRISPR/Cas9, showing its role in regulating translation through an allosteric mechanism.

1 citation

humanexperimental assay

𝕏 PostBluesky