Author

Clemency Jolly

The Francis Crick InstituteORCID 0000-0002-5869-635XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Adriana SalcedoiD· 1 shared Alex Buchanan· 1 shared Amit G. DeshwariD· 1 shared Charalampos RallisiD· 1 shared Christophe DessimoziD· 1 shared Daniel Charlton JeffaresiD· 1 shared David C. WedgeiD· 1 shared Dimitris AnastassiouiD· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Adriana SalcedoORCID

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2 papers

Recent·Most cited

Crowd-sourced benchmarking of single-sample tumour subclonal reconstruction

Adriana Salcedo, Maxime Tarabichi, Alex Buchanan, Shadrielle M. G. Espiritu, Hongjiu Zhang, Kaiyi Zhu, Tai-Hsien Ou Yang, Ignaty Leshchiner, Dimitris Anastassiou, Yuanfang Guan, Gun Ho Jang, Kerstin Haase, Amit G. Deshwar, William Zou, Imaad Umar, , Paul Christopher Boutros

The paper benchmarks 31 subclonal reconstruction algorithms on simulated tumours, finding that algorithm choice significantly impacts performance and no single algorithm excels across all tasks.

bioRxiv · Jun 14, 2022 · PreprintBioinformatics

Transient structural variations alter gene expression and quantitative traits in Schizosaccharomyces pombe.

Daniel Charlton Jeffares, Clemency Jolly, Mimoza Hoti, Doug Speed, Liam P. Shaw, Charalampos Rallis, François Balloux, Christophe Dessimoz, Jürg Bähler, Fritz Joachim Sedlazeck

The paper investigates how structural variations in yeast genomes affect gene expression and quantitative traits, finding that copy number variants significantly influence phenotypes and reproductive isolation.

Nature Communications · Jan 24, 2017Peer-reviewedGenomics