Mario Barrera Román

This paper introduces a microscopy-based method to measure tumour-specific viability in neuroblastoma co-cultures and patient samples, enabling more accurate drug response assessment.

This paper develops a human brainstem organoid model of H3.3K27M-altered DMG to study GD2 CAR T cell function and identify therapeutic targets.

BEHAV3D-TP is a computational framework for analyzing single-cell behavior in tumor microenvironments using intravital microscopy data, revealing migratory behaviors linked to specific TME components in diffuse midline glioma.

The paper evaluates how the functional avidity of anti-B7H3 CAR-T constructs relates to their ability to trigger effector function against tumors with varying antigen density.