Author

Penelope Dimas

Wellcome/MRC Cambridge Stem Cell InstituteORCID 0000-0002-5941-4828Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:ATAC-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Khalil S. RawjiiD· 2 shared Robin J.M. FrankliniD· 2 shared Amar SharmaiD· 1 shared Amber R. PhilpiD· 1 shared Amie K. WalleriD· 1 shared Bryan Hinrichsen· 1 shared Carlos Valenzuela‐KrugmanniD· 1 shared Carolina R. ReyesiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Khalil S. RawjiORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Dysregulation of transcription networks regulating oligodendrogenesis in age-related decline in CNS remyelination

Penelope Dimas, Samuel Morabito, Khalil S. Rawji, Qing Wang, Fynn N. Krause, Juan F. Cubillos, Néjma Belaadi, Peggy Assinck, Zechuan Shi, Zhenkun Cao, Holger Heyn, Riki Kawaguchi, Daniel H. Geschwind, Vivek Swarup, Robin J.M. Franklin

The paper identifies age-related dysregulation of transcription networks in oligodendrocyte differentiation using single-nucleus RNA and ATAC sequencing in mice, with parallels in MS lesions.

bioRxiv · Nov 14, 2025 · PreprintNeuroscience

Circulating Platelets Modulate Oligodendrocyte Progenitor Cell Differentiation During Remyelination

Amber R. Philp, Carolina R. Reyes, Josselyne B. Mansilla, Amar Sharma, Chao Zhao, Carlos Valenzuela‐Krugmann, Khalil S. Rawji, Ginez A. Gonzalez Martinez, Penelope Dimas, Bryan Hinrichsen, César Ulloa-Leal, Amie K. Waller, Diana M Bessa de Sousa, Maite A. Castro, Ludwig Aigner, , Francisco J. Rivera

This study shows platelets modulate OPC differentiation during remyelination, with transient exposure promoting and sustained exposure inhibiting differentiation in a mouse model of MS.

eLife · Nov 1, 2023Peer-reviewedNeuroscience