Author

Ludwig Aigner

Paracelsus Medical UniversityORCID 0000-0002-1653-8046Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Amar SharmaiD· 1 shared Amber R. PhilpiD· 1 shared Amie K. WalleriD· 1 shared Andrea WagneriD· 1 shared Andreas TrawegeriD· 1 shared Barbara KleiniD· 1 shared Benoit LehallieriD· 1 shared Bernhard IglsederiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperNeuroscience

Amar SharmaORCID

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Author profile →

3 papers

Recent·Most cited

Circulating Platelets Modulate Oligodendrocyte Progenitor Cell Differentiation During Remyelination

Amber R. Philp, Carolina R. Reyes, Josselyne B. Mansilla, Amar Sharma, Chao Zhao, Carlos Valenzuela‐Krugmann, Khalil S. Rawji, Ginez A. Gonzalez Martinez, Penelope Dimas, Bryan Hinrichsen, César Ulloa-Leal, Amie K. Waller, Diana M Bessa de Sousa, Maite A. Castro, Ludwig Aigner, , Francisco J. Rivera

This study shows platelets modulate OPC differentiation during remyelination, with transient exposure promoting and sustained exposure inhibiting differentiation in a mouse model of MS.

eLife · Nov 1, 2023Peer-reviewedNeuroscience

Allergy-induced systemic inflammation impairs tendon quality

Christine Lehner, Gabriel Spitzer, Patrick Benjamin Langthaler, Dominika Jakubecova, Barbara Klein, Nadja Weißenbacher, Andrea Wagner, Renate Gehwolf, Eugen Trinka, Bernhard Iglseder, Bernhard Paulweber, Ludwig Aigner, Sébastien Couillard‐Després, Richard Weiss, Herbert Tempfer, Andreas Traweger

This study investigates how allergy-induced systemic inflammation affects tendon quality and finds that it reduces tendon elasticity and alters matrix composition, with supporting epidemiological evidence linking allergies to increased tendinopathy risk.

EBioMedicine · Jan 1, 2022Peer-reviewedMolecular Biology

Lipid droplet accumulating microglia represent a dysfunctional and pro-inflammatory state in the aging brain

Julia Marschallinger, Tal Iram, Macy E. Zardeneta, Song Eun Lee, Benoit Lehallier, Michael Seamus Haney, John V. Pluvinage, Vidhu Mathur, Oliver Hahn, David W. Morgens, Justin Kim, Julia Tevini, Thomas Klaus Felder, Heimo Wolinski, Carolyn Ruth Bertozzi, , Tony Wyss‐Coray

The paper identifies lipid droplet-accumulating microglia (LAM) as a dysfunctional, pro-inflammatory state in aging brains, linked to neurodegeneration.

Nature Neuroscience · Jan 20, 2020Peer-reviewedNeuroscience