Julia Ladewig

This study uses human brain assembloids to show serotonergic innervation influences cortical progenitor states and proliferation during development.

This study develops a 2D system to generate human basal radial glia from iPSCs, showing they exhibit key molecular and functional features of native cells.

This study investigates SLC1A4 mutations in human iPSC-derived neurons, revealing metabolic and synaptic deficits linked to amino acid transport dysfunction and neurodevelopmental disorders.

The paper identifies two translocation modes for human fetal neural stem cells, showing that interphasic somal translocation (IST) accounts for 85% of their movement during cortical colonization.

This study uses LIS1-lissencephaly patient organoids to identify severity-dependent phenotypes and molecular mechanisms, and demonstrates that mTOR inhibitors can rescue disease-related changes.

This paper develops a Cas12a-based enrichment strategy and algorithm for nanopore sequencing to quantify repeat expansions and their methylation status.