Author

Franz-Josef Müller

Christian-Albrechts-Universität zu Kiel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Björn BrändliD· 3 shared Christian RohrandtiD· 3 shared Alexander MeissneriD· 2 shared Bernhard M. Schuldt· 2 shared Andreas SchuppertiD· 1 shared Andrew Heron· 1 shared Andy Wing Chun PangiD· 1 shared Ann C. BabtieiD· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Björn BrändlORCID

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4 papers

Recent·Most cited

Long-read nanopore sequencing reveals novel common genetic structural variants in Prader-Willi syndrome and associated psychosis

Maximilian Deest, Björn Brändl, Christian Rohrandt, Christian Karl Eberlein, Stefan Bleich, Franz-Josef Müller, Helge Frieling

This study uses long-read sequencing to identify novel structural variants in Prader-Willi syndrome patients, linking them to psychiatric traits and challenging current genetic hypotheses.

medRxiv · Jul 18, 2022 · PreprintGenetic & Genomic Medicine

Chromosome-level genome assembly of the functionally extinct northern white rhinoceros (Ceratotherium simum cottoni).

Gaojianyong Wang, Björn Brändl, Christian Rohrandt, Karl Hong, Andy Wing Chun Pang, Joyce Lee, Harris A. Lewin, Giovanna Migliorelli, Mario Stanke, Remy M Schwab, Sarah M. Ford, Iris Pollmann, Bernhard M. Schuldt, Marlys L. Houck, Oliver A. Ryder, , Marisa L. Korody

The paper generates a chromosome-level genome assembly for the functionally extinct northern white rhinoceros and compares it to the southern white rhinoceros.

bioRxiv · Dec 11, 2021 · PreprintGenomics

Repeat expansion and methylation state analysis with nanopore sequencing

Pay Gießelmann, Björn Brändl, Etienne Raimondeau, Rebecca Bowen, Christian Rohrandt, Rashmi Tandon, Helene Kretzmer, Günter Assum, Christina Galonska, Reiner Siebert, Ole Ammerpohl, Andrew Heron, Susanne A. Schneider, Julia Ladewig, Philipp Koch, , Franz-Josef Müller

This paper develops a Cas12a-based enrichment strategy and algorithm for nanopore sequencing to quantify repeat expansions and their methylation status.

bioRxiv · Nov 28, 2018 · PreprintGenetics

Stem cell differentiation is a stochastic process with memory

Patrick S. Stumpf, Rosanna C. G. Smith, Michael Lenz, Andreas Schuppert, Franz-Josef Müller, Ann C. Babtie, Thalia E. Chan, Michael P.H. Stumpf, Colin P. Please, Sam Howison, Fumio Arai, Ben D. MacArthur

This study shows that stem cell differentiation involves stochastic transitions through hidden microstates, revealing epigenetic memory and a statistical mechanics framework for cellular identity.

Cell Systems · Sep 1, 2017Peer-reviewedSystems Biology