Author

David McManus

MRC Laboratory of Molecular BiologyORCID 0000-0002-5984-369XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:electronic health records· 1 Organism:human· 1

Frequent Co-Authors

Aarti JagannathiD· 1 shared André FurgeriD· 1 shared Andrew P. PattoniD· 1 shared Emma L. MorrisiD· 1 shared Harry FischliD· 1 shared Huan WangiD· 1 shared Jane MelloriD· 1 shared Jason W. ChiniD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMolecular Biology

Aarti JagannathORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedMay 15, 2023

Astrocytic control of extra-cellular GABA drives circadian time-keeping in the suprachiasmatic nucleus

Andrew P. Patton, Emma L. Morris, David McManus…·Michael Harvey Hastings

The paper shows that astrocytic GABA transporters regulate extracellular GABA levels in the SCN, which in turn controls circadian time-keeping through neuronal inhibition.

58 citationstop 1%

mouseelectronic health records

𝕏 PostBluesky

Molecular BiologyThe EMBO JournalPeer-reviewedOct 9, 2020

Cold induced chromatin compaction and nuclear retention of clock mRNAs resets the circadian rhythm

Harry Fischl, David McManus, Roel Oldenkamp…·André Furger

The paper shows that cold exposure causes chromatin compaction and nuclear retention of circadian clock transcripts, which resets the circadian rhythm upon rewarming.

25 citations

humanbulk RNA-seq

𝕏 PostBluesky