Author
Peking UniversityORCID 0000-0002-7472-0057Unclaimed ORCID profile · follow to get notified of new preprints
12 papers
Recent·Most cited
Huan Wang, Yuqi Yan, Yulin Zhao, Di Wang, Changhao Huang, Yulong Li
The paper introduces a method to create excitation ratiometric neuropeptide sensors with improved sensitivity for in vivo use by using dual excitation and fluorescence correction.
bioRxiv · Sep 23, 2026 · PreprintNeuroscience
Yan‐Jiao Wu, Xue Gu, Yalei Kong, Shuo Yang, Huan Wang, Miao Xu, Qi Wang, Xin Yi, Ze-Jie Lin, Zhi-Han Jiao, Hoiyin Cheung, Xin-Yu Zhao, Xin Bian, Qin Jiang, Ying Xiao Li, , Tian‐Le Xu
The paper identifies NPY+ interneurons in the ventral hippocampus that regulate memory extinction through distinct sub-ensembles via fast and slow inhibition.
Nature Neuroscience · Mar 31, 2026Peer-reviewedNeuroscience
Yizhou Zhuo, Bin Luo, Xinyang Yi, Hui Dong, Xiaolei Miao, Jinxia Wan, John T. Williams, Malcolm G. Campbell, Ruyi Cai, Tongrui Qian, Fengling Li, Sophia J. Weber, Lei Wang, Bozhi Li, Yu Wei, , Yulong Li
The paper develops improved GRABDA sensors to monitor dopaminergic activity in vivo, showing high sensitivity and spatially resolved DA release in mice during behaviors.
Nature Methods · Nov 30, 2023Peer-reviewedNeuroscience
Huan Wang, Tongrui Qian, Yulin Zhao, Yizhou Zhuo, Chunling Wu, Takuya Osakada, Peng Chen, Zijun Chen, Huixia Ren, Yuqi Yan, Lan Geng, Shengwei Fu, Long Mei, Guochuan Li, Ling Wu, , Yulong Li
The paper develops GRAB sensors for detecting neuropeptides with high specificity and sensitivity, enabling in vivo monitoring of their release and function.
Science · Nov 16, 2023Peer-reviewedNeuroscience
Jiesi Feng, Hui Dong, Julieta E. Lischinsky, Jingheng Zhou, Fei Deng, Chaowei Zhuang, Xiaolei Miao, Huan Wang, Hao Xie, Guohong Cui, Dayu Lin, Yulong Li
This paper develops improved GRABNE sensors to monitor norepinephrine release in vivo with high sensitivity and uses them to study NE dynamics in mice.
bioRxiv · Jun 22, 2023 · PreprintNeuroscience
Andrew P. Patton, Emma L. Morris, David McManus, Huan Wang, Yulong Li, Jason W. Chin, Michael Harvey Hastings
The paper shows that astrocytic GABA transporters regulate extracellular GABA levels in the SCN, which in turn controls circadian time-keeping through neuronal inhibition.
Proceedings of the National Academy of Sciences · May 15, 2023Peer-reviewedNeuroscience
Zhaofa Wu, Yuting Cui, Huan Wang, Hao Wu, Yi Wan, Bohan Li, Lei Wang, Sunlei Pan, Wanling Peng, Ao Dong, Zhengwei Yuan, Miao Jing, Min Xu, Minmin Luo, Yulong Li
The paper develops a genetically encoded adenosine sensor to show activity-dependent non-vesicular adenosine release from somatodendritic regions via calcium influx and equilibrative transporters.
Proceedings of the National Academy of Sciences · Mar 30, 2023Peer-reviewedNeuroscience
Hui Dong, Mengyao Li, Yuqi Yan, Tongrui Qian, Yunzhi Lin, Xiaoyuan Ma, Henry F. Vischer, Can Liu, Guochuan Li, Huan Wang, Rob Leurs, Yulong Li
This paper develops genetically encoded sensors to measure histamine release in vitro and in vivo, showing high sensitivity and specificity for extracellular histamine detection.
Neuron · Mar 15, 2023Peer-reviewedNeuroscience
Tongrui Qian, Huan Wang, Peng Wang, Lan Geng, Long Mei, Takuya Osakada, Lei A. Wang, Yan Tang, Alan Kania, Valery Grinevich, Ron Stoop, Dayu Lin, Minmin Luo, Yulong Li
The paper develops a new oxytocin sensor to study compartmental OT release in neurons and finds distinct calcium channel roles and fusion machinery differences in axons and somatodendritic regions.
Nature Biotechnology · Jan 2, 2023Peer-reviewedNeuroscience
Zhaofa Wu, Kaikai He, Yue Chen, Hongyu Li, Sunlei Pan, Bohan Li, Tingting Liu, Fengxue Xi, Fei Deng, Huan Wang, Jiulin Du, Miao Jing, Yulong Li
The paper develops an ultrasensitive GRABATP1.0 sensor to detect extracellular ATP in real time, demonstrating its use in vitro and in vivo across multiple conditions.
Neuron · Dec 22, 2021Peer-reviewedNeuroscience
Ao Dong, Kaikai He, Barna Dudok, Jordan S. Farrell, Wuqiang Guan, Daniel J. Liput, Henry L. Puhl, Ruyi Cai, Huan Wang, Jiali Duan, Eddy Albarran, Jun Ding, David M. Lovinger, Bo Li, Iván Soltész, Yulong Li
The paper introduces a genetically encoded fluorescent sensor, GRABeCB2.0, to measure endocannabinoid dynamics with high spatiotemporal resolution in vitro and in vivo, revealing new insights into eCB signaling in neurons and brain regions.
Nature Biotechnology · Nov 11, 2021Peer-reviewedNeuroscience
Fangmiao Sun, Jianzhi Zeng, Miao Jing, Jingheng Zhou, Jiesi Feng, Scott F. Owen, Yichen Luo, Funing Li, Huan Wang, Takashi Yamaguchi, Zi-hao Yong, Yijing Gao, Wanling Peng, Lizhao Wang, Siyu Zhang, , Yulong Li
This paper develops GRABDA sensors to measure dopamine with high precision in multiple organisms during complex behaviors.
Cell · Jul 1, 2018Peer-reviewedNeuroscience