Harry Fischl

This study shows that inhibiting METTL3 with STC-15 causes RNA misprocessing, leading to dsRNA formation and activation of innate immunity in cancer cells.

This study shows Spt4 regulates RNA polymerase II elongation and nucleosome positioning in yeast by facilitating movement through the +2 nucleosomal barrier.

The paper investigates the transcriptional response to acute stress in yeast, identifying two components: dynamic +1 nucleosome positioning and global Pol2 stalling leading to early transcription termination.

This paper introduces SNU-Seq and sf4sU-Seq methods to map nascent transcripts at single-nucleotide resolution, revealing transcriptional responsiveness in an epigenetically primed human genome.

The paper shows that cold exposure causes chromatin compaction and nuclear retention of circadian clock transcripts, which resets the circadian rhythm upon rewarming.

The paper investigates the relationship between H3K4me3 and transcription, finding no direct instructive or informative link between the two on a genome-wide scale in budding yeast.