Author

Deokho Lee

Keio UniversityORCID 0000-0002-5992-9039Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3

Frequent Co-Authors

Kazuno NegishiiD· 3 shared Toshihide KuriharaiD· 3 shared Chiho Shoda· 2 shared Hiroyuki NakashizukaiD· 2 shared Satoru YamagamiiD· 2 shared Akiharu KuboiD· 1 shared Ayaka Nakai· 1 shared Heonuk JeongiD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMolecular Biology

Kazuno NegishiORCID

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3 papers

Recent·Most cited

Inhibition of hypoxia-inducible factors suppresses subretinal fibrosis

Chiho Shoda, Deokho Lee, Yukihiro Miwa, Satoru Yamagami, Hiroyuki Nakashizuka, Kazumi Nimura, Kazutoshi Okamoto, Hirokazu Kawagishi, Kazuno Negishi, Toshihide Kurihara

This study shows that inhibiting hypoxia-inducible factors suppresses subretinal fibrosis in AMD, suggesting potential therapeutic strategies.

The FASEB Journal · Jul 2, 2024Peer-reviewedMolecular Biology

Tight junction component protein claudin-1 deficiency in retinal pigment epithelium leads to early and intermediate age-related macular degeneration phenotypes in mice.

Ayaka Nakai, Deokho Lee, Yan Zhang, Chiho Shoda, Tetsu Imanishi, Heonuk Jeong, Shin‐ichi Ikeda, Kazuno Negishi, Hiroyuki Nakashizuka, Satoru Yamagami, Akiharu Kubo, Toshihide Kurihara

This study shows that claudin-1 deficiency in mouse retinal pigment epithelium leads to AMD-like phenotypes including drusenoid deposits and pigment abnormalities.

bioRxiv · Dec 7, 2023 · PreprintMolecular Biology

Starburst amacrine cells amplify optogenetic visual restoration through gap junctions in the murine retina

Yusaku Katada, Hiromitsu Kunimi, Naho Serizawa, Deokho Lee, Kenta Kobayashi, Kazuno Negishi, Hideyuki Okano, Kenji F. Tanaka, Kazuo Tsubota, Toshihide Kurihara

The paper demonstrates that optogenetic actuators in starburst amacrine cells enhance visual restoration in murine retinas through gap junctions.

Molecular Therapy — Methods & Clinical Development · May 11, 2023Peer-reviewedNeuroscience