Cancer BiologyNature CommunicationsPeer-reviewed
Enhanced Tumor Control and Hearing Loss Prevention Achieved with Combined Immune Checkpoint Inhibitor and Anti-VEGF Therapy in Vestibular Schwannoma Model
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Author
Harvard UniversityORCID 0000-0002-6022-5661Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Zhenzhen Yin, Simeng Lu, Limeng Wu…·Lei Xu
This study shows that combining anti-PD1 treatment with radiation therapy for vestibular schwannomas improves tumor control, reduces radiation dose, and elicits systemic anti-tumor effects.
Zhenzhen Yin, Limeng Wu, Yanling Zhang…·Lei Xu
This study identifies IL-6 and EGFR signaling as therapeutic targets for schwannomatosis, showing combined blockade reduces both pain and tumor growth in preclinical models.