Author

Limeng Wu

Harvard UniversityORCID 0000-0002-9382-6447Unclaimed ORCID profile · follow to get notified of new preprints

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Limeng Wu1 paper

Biology Disciplines

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Cancer Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alona MuzikanskyiD· 3 shared Lei XuiD· 3 shared Scott Randall PlotkiniD· 3 shared William W. HoiD· 3 shared Yao SuniD· 3 shared Zhenzhen YiniD· 3 shared Adam P. JonesiD· 2 shared Bingyu Xiu· 2 shared

Activity by Year

2023-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Alona MuzikanskyORCID

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3 papers

Recent·Most cited

Enhanced Tumor Control and Hearing Loss Prevention Achieved with Combined Immune Checkpoint Inhibitor and Anti-VEGF Therapy in Vestibular Schwannoma Model

Simeng Lu, Zhenzhen Yin, Limeng Wu, Yao Sun, Jie Chen, Lai Man Natalie Wu, Janet L. Oblinger, Day Caven Blake, Bingyu Xiu, Lukas David Landegger, Richard Seist, William W. Ho, Adam P. Jones, Alona Muzikansky, Konstantina M. Stanković, , Lei Xu

Nature Communications · Feb 11, 2026Peer-reviewedCancer Biology

Direct and abscopal anti-tumor responses elicited by peripheral nerve schwannoma irradiation synergize with anti-PD1 treatment in vestibular schwannoma models

Zhenzhen Yin, Simeng Lu, Limeng Wu, Yao Sun, David W. Blake, Jie Chen, Lukas David Landegger, William W. Ho, Bingyu Xiu, Adam P. Jones, Alona Muzikansky, Helen Alice Shih, Konstantina M. Stanković, Scott Randall Plotkin, Lei Xu

This study shows that combining anti-PD1 treatment with radiation therapy for vestibular schwannomas improves tumor control, reduces radiation dose, and elicits systemic anti-tumor effects.

bioRxiv · Dec 29, 2024 · PreprintCancer Biology

Co-Targeting IL-6 and EGFR signaling for the treatment of schwannomatosis and associated pain

Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, John W. Chen, Sonu Subudhi, William W. Ho, Grace Y. Lee, Athena Ching‐Jung Wang, Xing Gao, Jun P. Ren, Chao Zhu, Na Zhang, Gino B. Ferraro, Alona Muzikansky, , Lei Xu

This study identifies IL-6 and EGFR signaling as therapeutic targets for schwannomatosis, showing combined blockade reduces both pain and tumor growth in preclinical models.

bioRxiv · Feb 6, 2023 · PreprintNeuroscience