Sergi Cervilla

RNA and protein are not interchangeable in single-cell spatial multi-omics

This study shows that spatial RNA and protein measurements are largely overlapping for lineage markers and abundance but discordant for specific molecules and spatial features, indicating they are complementary rather than interchangeable.

A pan-cancer single-cell atlas of pericytes

The paper constructs a pan-cancer single-cell RNA sequencing atlas of pericytes, revealing a common transcriptional program in tumour-associated pericytes and their specialised subtypes across multiple cancers.

Convergent stromal and immune remodeling defines spatial tumor dynamics in PARP inhibitor-resistant high-grade serous ovarian cancer

This study identifies spatial tumor microenvironment changes in PARP inhibitor-resistant high-grade serous ovarian cancer using spatial transcriptomics.

Benchmarking of spatial transcriptomics platforms across six cancer types

This study benchmarks spatial transcriptomics and proteomics platforms across six cancer types, identifying platform-specific strengths and limitations in data quality and biological insights.