Author

Julieta Aprea

DRESDEN-concept Genome CenterORCID 0000-0002-8749-7878Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Andreas DahliD· 2 shared Anna‐Lena BörschiD· 1 shared Anne Kathrin MausbergiD· 1 shared Anne‐Kathrin Uerschels· 1 shared Beatrice WasseriD· 1 shared Bianca Eggert· 1 shared Carina FabianiD· 1 shared Carolina ThomasiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Andreas DahlORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multi-omic characterization of human sural nerves acrosspolyneuropathies

Michael Heming, Anna‐Lena Börsch, Jolien Wolbert, Christian Thomas, Anne Kathrin Mausberg, Fabian Szepanowski, Bianca Eggert, I‐Na Lu, Julia Tietz, Finja S.V. Dienhart, Maja Meschnark, Jan‐Kolja Strecker, Michael Glatza, Carolina Thomas, Noemi Gmahl, , Gerd Meyer zu Hörste

The paper integrates single nuclei transcriptomics and spatial transcriptomics of human peripheral nerves to identify novel cell markers, reveal pan-nerve disease characteristics, and demonstrate potential for unbiased diagnostic classification.

Nature Communications · Aug 23, 2025Peer-reviewedNeuroscience

EGFL7 promotes immune evasion in glioblastoma by interaction with integrin β2

Sukrit Mahajan, Philipp Abe, Fanny Ehret, Carina Fabian, Nora Heinig, Marc Gentzel, Rajinder Gupta, Julieta Aprea, Paul Warnke, Eirini Moysoglou, Beatrice Wasser, Stephan Grabbe, Andreas Dahl, Kathrin Barth, Marc Schmitz, , Mirko H. H. Schmidt

This study identifies EGFL7 as a driver of immune evasion in glioblastoma by interacting with integrin β2, showing that targeting this axis enhances immunotherapy efficacy.

bioRxiv · Jul 28, 2025 · PreprintCancer Biology

Benchmarking of spatial transcriptomics platforms across six cancer types

Sergi Cervilla, Daniela Grases, Elena Perez, Francisco X. Real, Eva Musulén, Julieta Aprea, Manel Esteller, Eduard Porta‐Pardo

This study benchmarks spatial transcriptomics and proteomics platforms across six cancer types, identifying platform-specific strengths and limitations in data quality and biological insights.

bioRxiv · May 21, 2024 · PreprintGenomics