Author

Tamara Maiuri

McMaster UniversityORCID 0000-0002-6103-5835Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Carlos Barba BazaniD· 2 shared Ray TruantiD· 2 shared Anthony K. L. LeungiD· 1 shared C.H. ArrowsmithiD· 1 shared Christina Yi PengiD· 1 shared Edward J. WildiD· 1 shared Elizabeth J. OsterlundiD· 1 shared Filipe Brogueira RodriguesiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Carlos Barba BazanORCID

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2 papers

Recent·Most cited

Direct Measure of DNA Damage in Huntington Disease Reveals Elevated Oxidative Genotoxic Stress and Dysfunctional DNA Repair

Carlos Barba Bazan, Samantha R Laville-Dupuy, Maya Klepfish, J. Cousineau, Tamara Maiuri, Christina Yi Peng, Elizabeth J. Osterlund, Melanie Alpaugh, Ray Truant

This study uses RADD to directly measure oxidative DNA damage in HD cells, revealing elevated DNA damage and dysfunctional DDR pathways.

bioRxiv · Nov 21, 2025 · PreprintCell Biology

Poly ADP-Ribose Signaling is Dysregulated in Huntington Disease Patients

Tamara Maiuri, Carlos Barba Bazan, Rachel Harding, Nola Begeja, Tae‐In Kam, Lauren M. Byrne, Filipe Brogueira Rodrigues, Monica M Warner, Kaitlyn Neuman, Muqtasid Mansoor, Mohsen Badiee, Morgan Dasovich, Keona Q. Wang, Leslie Michels Thompson, Anthony K. L. Leung, , Ray Truant

The paper identifies a deficient PAR response in Huntington disease patients, suggesting a potential therapeutic target for early intervention.

Proceedings of the National Academy of Sciences · Sep 27, 2024Peer-reviewedNeuroscience