Author
Jun Yao
The University of Texas at AustinORCID 0000-0002-1232-1587Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2018-2025 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 19 mutual co-author links12 papers
Recent·Most cited
- Molecular BiologybioRxivPreprint4 citations
- Molecular BiologyPLoS GeneticsPeer-reviewed
Human cells contain myriad excised linear intron RNAs with links to gene regulation and potential utility as biomarkers
Jun Yao, Hengyi Xu, Elizabeth A. Ferrick-Kiddie…·Alan M. Lambowitz
The paper identifies thousands of FLEXIs in human cells, links them to RNA-binding proteins, and suggests their potential as biomarkers.
7 citations - Molecular BiologyScience AdvancesPeer-reviewed
Mechanisms used for cDNA synthesis and site-specific integration of RNA into DNA genomes by a reverse transcriptase-Cas1 fusion protein
Georg Mohr, Jun Yao, Seung Kuk Park…·Alan M. Lambowitz
The paper identifies mechanisms by which an RT-Cas1 fusion protein integrates RNA into DNA genomes through cDNA synthesis and site-specific integration.
5 citations - GenomicsMolecular Ecology ResourcesPeer-reviewed
Pan-genome analysis highlights the role of structural variation in the evolution and environmental adaptation of Asian honeybees
Li Yancan, Jun Yao, Huiling Sang…·Cheng Sun
This study constructs the first pan-genome of Asian honeybees using long-read sequencing and identifies structural variations linked to environmental adaptation.
- Genetic & Genomic MedicinemedRxivPreprint
TGIRT-seq of Inflammatory Breast Cancer Tumor and Blood Samples Reveals Widespread Enhanced Transcription Impacting RNA splicing and Intronic RNAs in Plasma
Dennis Wylie, Xiaoping Wang, Jun Yao…·Alan M. Lambowitz
This study uses TGIRT-seq to analyze IBC tumor and blood samples, revealing widespread transcriptional changes and RNA splicing impacts in plasma.
5 citations - Developmental BiologybioRxivPreprint
Activation of an injury-associated transient progenitor state in the epicardium is required for zebrafish heart regeneration
Yu Xia, Sierra Duca, Björn Perder…·Jingli Cao
The paper identifies a transient epicardial progenitor cell population in zebrafish that is essential for heart regeneration through single-cell RNA sequencing and functional analysis.
- Molecular BiologybioRxivPreprint
Group II Intron-Like Reverse TranscriptasesFunction in Double-Strand Break Repair by Microhomology-Mediated End Joining
Seung Kuk Park, Georg Mohr, Jun Yao…·Alan M. Lambowitz
The paper identifies a bacterial group II intron-like reverse transcriptase involved in DNA repair via microhomology-mediated end joining.
DOI 10.1101/2022.03.14.484287 - GenomicseLifePeer-reviewed
Identification of protein-protected mRNA fragments and structured excised intron RNAs in human plasma by TGIRT-seq peak calling
Jun Yao, Douglas C. Wu, Ryan M. Nottingham, Alan M. Lambowitz
31 citations - Molecular BiologyJournal of Biological ChemistryPeer-reviewed
Template switching by a group II intron reverse transcriptase: biochemical analysis and implications for RNA-seq
Alfred M. Lentzsch, Jun Yao, Rick Russell, Alan M. Lambowitz
The paper analyzes template switching by a group II intron reverse transcriptase, establishing kinetic parameters and identifying conditions for efficient acceptor RNA/DNA capture.
- GenomicsScientific ReportsPeer-reviewed
Improved TGIRT-seq methods for comprehensive transcriptome profiling with decreased adapter dimer formation and bias correction
Hengyi Xu, Jun Yao, Douglas C. Wu, Alan M. Lambowitz
The paper improves TGIRT-seq methods by reducing adapter dimer formation and correcting 5- and 3-end biases, enhancing transcriptome coverage and library construction efficiency.
75 citations - Molecular BiologyeLifePeer-reviewed
Pericentromeric hypomethylation elicits an interferon response in an animal model of ICF syndrome
Srivarsha Rajshekar, Jun Yao, Paige K. Arnold…·Mary Grace Goll
This study shows that pericentromeric hypomethylation in zebrafish triggers an interferon response, linking it to ICF syndrome-like phenotypes.
45 citations - BioinformaticsBMC GenomicsPeer-reviewed
Limitation of alignment-free tools in total RNA-seq quantification
Douglas C. Wu, Jun Yao, Kevin S. Ho…·Claus O. Wilke
This study compares alignment-free and alignment-based RNA-seq pipelines for total RNA quantification, finding alignment-free tools less accurate for small and lowly-expressed RNAs.
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