Maria Irene Kontaridis

This study identifies somatic Ras-MAPK pathway variants in hippocampal tissue from patients with drug-resistant epilepsy, showing their association with clonal competition and worse surgical outcomes.

This study identifies MYRF's critical role in epicardial development and links its deficiency to cardiac abnormalities in CUGS.

This paper shows rigosertib reverses hypertrophic cardiomyopathy in RAF1-associated Noonan syndrome using Drosophila, iPSC, and mouse models.

This study shows that deleting PTP1B in cardiomyocytes protects against high-fat diet-induced heart disease by promoting fatty acid metabolism and reducing glucose metabolism through a novel PTP1B/PKM2/AMPK axis.