Author

Zhen Xiao

Southern University of Science and TechnologyORCID 0000-0002-6132-6149Unclaimed ORCID profile · follow to get notified of new preprints

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Zhen Xiao1 paper

Biology Disciplines

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Cell Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2

Frequent Co-Authors

Andrew P. HutchinsiD· 3 shared Gang MaiD· 3 shared Jianfei XuiD· 2 shared Lin ZhengiD· 2 shared Xiuling Fu· 2 shared Xuemeng ZhouiD· 2 shared Yu QiaoiD· 2 shared Zhangting Liang· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCell Biology

Andrew P. HutchinsORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 10, 2026

SALL2 constrains TEAD4 by maintaining repressive chromatin to restrict trophectoderm identity

Yu Qiao, Jianfei Xu, Lin Zheng…·Andrew P. Hutchins

This study shows SALL2 restricts trophectoderm identity by maintaining repressive chromatin at TEAD4-bound loci, preventing TE lineage commitment in human pluripotent stem cells.

DOI 10.64898/2026.07.10.737659

𝕏 PostBluesky

GenomicsNature CommunicationsPeer-reviewedAug 18, 2025

Transposable Element Expression and Sub-cellular Dynamics During hPSC Differentiation to Endoderm, Mesoderm, and Ectoderm Lineages

Isaac A. Babarinde, Xiuling Fu, Gang Ma…·Andrew P. Hutchins

This study examines TE expression and sub-cellular dynamics during hPSC differentiation to endoderm, mesoderm, and ectoderm lineages, revealing lineage-specific TE expression patterns and chromatin associations.

4 citations

humanlong-read sequencing

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Cell BiologyAdvanced SciencePeer-reviewedDec 10, 2024

BRD8 guards the pluripotent state by sensing and maintaining histone acetylation

Li Sun, Xiuling Fu, Zhen Xiao…·Andrew P. Hutchins

This study shows BRD8 maintains pluripotency by sensing and maintaining histone acetylation, preventing the conversion of primed EpiSCs to naive ESCs.

7 citations

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