Kaelan R. Sullivan

This study identifies Arc as critical for packaging tau into extracellular vesicles, facilitating its release and intercellular transmission in Alzheimer's disease.

This study shows that dArc genes in Drosophila melanogaster regulate sugar reward valuation through capsid-mediated intercellular communication, affecting associative learning and reward valuation.

This study shows Arc EVs mediate intercellular synaptic plasticity through IRSp53-dependent biogenesis, leading to loss of surface AMPA receptors in neighboring dendrites.

This study identifies a Hedgehog-FGF signaling axis critical for anterior mesoderm patterning during gastrulation using single-cell transcriptomics in Hh-deficient embryos.