Mervenaz Koska

This study investigates how promoter strength and position influence promoter competition by inserting diverse promoters into the Sox2 locus and measuring their effect on endogenous Sox2 expression.

The paper shows how DNA motifs guide transcription factor cooperativity in embryonic face and limb mesenchyme, shaping cell identity and morphology.

This study identifies Hedgehog signaling as a regulator of differentiation timing through a heterochronic gene regulatory network in cardiac and neural lineages.

This study identifies a Hedgehog-FGF signaling axis critical for anterior mesoderm patterning during gastrulation using single-cell transcriptomics in Hh-deficient embryos.