Mark Bathe

DNA origami particles displaying eOD-GT8 with a synthetic T helper epitope gave antigen-focused germinal centers and expanded VRC01-class precursors in humanized mice after one immunization.

This paper develops a method to precisely place colloidal quantum emitters on photonic chips using DNA origami, enabling nanometer-scale integration and single-photon emission.

This paper uses multimodal synaptomics to study how ketamine-induced changes in synaptic proteins and activity relate to schizophrenia models.

The paper introduces SEARCH-MaP and SEISMIC-RNA to discover and quantify long-range RNA base pairs in coronaviruses, revealing their role in ribosomal frameshifting.

The paper uses PRISM to analyze how knocking down 16 autism and schizophrenia genes affects synaptic protein distributions and constructs a causal network model.

The paper uses multiplexed fluorescence imaging and machine learning to identify synaptic subtypes and examine their changes under activity suppression.

The paper introduces PRISM, a method for multiplexed imaging of synaptic proteins, enabling high-throughput quantification of co-expression and nanometer-scale organization.