Jesse S. Plung

The paper uses a pro-apoptotic CRISPR screening strategy in mosquito cells to identify Lachesin as a critical CHIKV entry factor.

This study identifies the molecular basis of chikungunya virus recognition of the mosquito-specific receptor Lachesin using cryo-EM structures and shows a Lachesin polymorphism that blocks virus entry.

This study identifies Lachesin as a mosquito receptor for multiple arthritogenic alphaviruses using CRISPR screening in Aedes albopictus cells.

The paper identifies the HUSH complex as a regulator of EBV-transformed B cell sensitivity to NK cell surveillance by repressing the NKG2A ligand γ-protocadherin.

The paper identifies receptor-binding polymorphisms in WEEV that explain shifts in receptor dependencies and enable nonpathogenic strains to infect neurons.

The paper introduces SEARCH-MaP and SEISMIC-RNA to discover and quantify long-range RNA base pairs in coronaviruses, revealing their role in ribosomal frameshifting.