Cancer BiologybioRxivPreprint
Decoding the BRCA2 reversion principles underlying PARP inhibitor resistance
Anna Horacek, Frances Li Kueper, Robert Lu…·Dirk F. Hockemeyer
The paper identifies principles governing BRCA2 reversion mutations that confer resistance to PARP inhibitors using CRISPR editing and an isogenic cell system.
DOI 10.64898/2026.04.29.721733