Author

Anna Horacek

University of California, BerkeleyORCID 0000-0002-5984-9434Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alina SalageaniD· 1 shared Cordell J. ClarkiD· 1 shared Diana E. LibudaiD· 1 shared Dirk F. HockemeyeriD· 1 shared Erik ToraasoniD· 1 shared Frances Li Kueper· 1 shared Francesca ColeiD· 1 shared Hanqin LiiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Alina SalageanORCID

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2 papers

Recent·Most cited

Decoding the BRCA2 reversion principles underlying PARP inhibitor resistance

Anna Horacek, Frances Li Kueper, Robert Lu, Isabella Paige Lamont, Stella Tran, Hanqin Li, Dirk F. Hockemeyer

The paper identifies principles governing BRCA2 reversion mutations that confer resistance to PARP inhibitors using CRISPR editing and an isogenic cell system.

bioRxiv · May 10, 2026 · PreprintCancer Biology

Sister chromatid repair maintains genomic integrity during meiosis in Caenorhabditis elegans

Erik Toraason, Anna Horacek, Cordell J. Clark, Marissa L. Glover, Victoria L. Adler, Tolkappiyan Premkumar, Alina Salagean, Francesca Cole, Diana E. Libuda

The paper demonstrates that sister chromatid repair occurs during meiosis in C. elegans, with noncrossovers being the predominant recombination outcome and specific proteins required at different stages.

Current Biology · Mar 19, 2021Peer-reviewedGenetics