Eyal Banin

This study compares wavelet transform and short-time Fourier transform for analyzing electroretinographic oscillatory potentials, finding wavelet transform provides better time-frequency resolution and disease-specific insights.

The paper develops an in vitro method to study how guide RNAs affect RNA editing and splicing, finding that editing can both disrupt and improve splicing outcomes depending on the target site.

This paper develops a single therapeutic molecule targeting the most common class of nonsense variants in inherited retinal diseases using anticodon-edited tRNA.

This study identifies Smarcc1's role in optic stalk development and optic nerve head astrocyte differentiation, showing its necessity for morphogenesis and RGC survival.

The paper identifies de novo and inherited variants in U4 and U6 snRNAs causing retinitis pigmentosa and shows their impact on snRNP biogenesis.

This study identifies aberrant splicing caused by the NR2E3 c.932G>A mutation and shows that splice-shifting ASOs can restore full-length protein function.

This study fine-tunes FAM161A gene therapy in mice to restore retinal function by optimizing promoter activity, dosage, and isoform delivery.

The paper identifies INPP5E variants in non-syndromic retinal degenerations, expanding the known phenotypic spectrum of this ciliary gene.

The paper identifies pathogenic deep-intronic and structural variants in 26% of unsolved Stargardt disease cases using integrated genomics and transcriptomics.