Olivier Mercey

This study identifies DCX as essential for microtubule branching in Plasmodium falciparum gametocytes, which is required for mosquito transmission, independent of its role in the conoid.

This study evaluates gene supplementation of MYO7A via dual AAVs and CRISPR/Cas activation of Myo7b in animal models and human retinal organoids to treat Usher syndrome 1B.

The paper introduces HAK-actin, a probe for imaging actin cytoskeleton compatible with U-ExM, showing robust staining across human cells, microbial eukaryotes, and mouse retinal tissue.

This study provides a molecular and structural map of the ciliary base in mammalian multiciliated cells using advanced imaging and molecular techniques.

This study uses cryo-expansion microscopy to visualize the nanoscale architecture of immune synapses in T cells and their interactions with tumor cells, revealing structural details of signaling molecules and lytic granules.

This study shows that TMEM67 is essential for proper dorsal spinal cord patterning in human organoids, with loss of TMEM67 disrupting interneuron specification and altering BMP4 signaling.

This study identifies C2CD3 as a radial organizer of the distal centriole and appendages, revealing its role in structuring the luminal ring and interacting with the DISCO complex.

This study shows that glutamylation imbalance in photoreceptor cells leads to structural defects and degeneration, highlighting its role in maintaining outer segment architecture.

This study fine-tunes FAM161A gene therapy in mice to restore retinal function by optimizing promoter activity, dosage, and isoform delivery.

This study shows the MCC cell cycle variant accelerates centriole biogenesis by overlapping two cycles to produce multiple mature centrioles without cell division.

This study uses expansion microscopy to investigate LCA5-related photoreceptor defects and evaluates gene therapy efficacy in a mouse model.