Author

Michael Screen

Babraham InstituteORCID 0000-0002-6290-9215Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alex J. WhaleiD· 2 shared Fiamma SalernoiD· 2 shared Louise S. MathesoniD· 2 shared Melanie StammersiD· 2 shared Claudia Ribeiro de AlmeidaiD· 1 shared Daniel James HodsoniD· 1 shared Davide Maria VespasianiiD· 1 shared Deniz Akdeniz· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

Alex J. WhaleORCID

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2 papers

Recent·Most cited

ImmunologyScience ImmunologyPeer-reviewedOct 31, 2025

RNA-binding proteins control the G2-M checkpoint of the germinal centre B cell

Fiamma Salerno, Alex J. Whale, Louise S. Matheson…·Martin Turner

This study identifies ZFP36L1 and ZFP36L2 as RNA-binding proteins that regulate the G2-M checkpoint in GC B cells to prevent replication stress and maintain genome stability.

14 citationstop 5%

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintJan 10, 2025

RNA helicase DDX1 regulates germinal centre selection and affinity maturation by promoting tRNA ligase activity

Rachael Kimber, Sarah Ingelsfield, Michael Screen…·Claudia Ribeiro de Almeida

This study shows DDX1 promotes B-cell proliferation in germinal centres by enhancing mRNA translation through tRNA ligase activity, crucial for affinity maturation.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky