Author

Sumirtha Balaratnam

National Cancer InstituteORCID 0000-0002-6339-2318Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CITE-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1 Organism:yeast· 1

Frequent Co-Authors

John S. SchneeklothiD· 2 shared Andrej LuptákiD· 1 shared Brandon LatifiiD· 1 shared Christopher D. Sibley· 1 shared Desta Doro BumeiD· 1 shared Jennifer A. PrescheriD· 1 shared Mo YangiD· 1 shared Peri R. PrestwoodiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

John S. SchneeklothORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 10, 2025

Discovery of small molecule probes targeting the 5' stem-loop in the yeast U4/U6 snRNA

Mo Yang, Shaifaly Parmar, Sumirtha Balaratnam…·John S. Schneekloth

This paper identifies small molecule ligands targeting the K-turn region of the yeast U4/U6 snRNA using a structure-based screening approach and validates their binding effects.

DOI 10.1101/2025.10.10.681657

yeastCITE-seq

𝕏 PostBluesky

BiochemistryACS Chemical BiologyPeer-reviewedDec 6, 2024

Bioorthogonal cyclopropenones for investigating RNA structure

Wen Chen, Christopher D. Sibley, Brandon Latifi…·Jennifer A. Prescher

This paper develops bioorthogonal cyclopropenones to crosslink RNA and study its native structures in cells.

3 citations

experimental assay

𝕏 PostBluesky