Selina K. Jorch

This study identifies renal mononuclear phagocytes as an intracellular reservoir for UPEC in pyelonephritis, showing that complement receptor-mediated entry promotes bacterial persistence and limits β-lactam efficacy.

This study identifies lactate as a metabolic driver of CD163+ macrophage polarization in human pyelonephritis, linking lactate metabolism to immune dysfunction.

This study shows that the CCR4/CCL17 axis promotes intestinal acute GvHD by recruiting T cells and increasing Gata3 expression, and identifies ruxolitinib as a potential therapeutic.