Li Tang

This paper shows that IL-21-Fc reprograms NK cell metabolism to enhance their function against MHC-I deficient tumors, leading to tumor eradication in preclinical models.

This paper designs switchable cytokines that are activated by Venetoclax, showing tumor control comparable to native cytokines and enhancing therapeutic safety.

The paper develops caffeine-inducible systems for controlling gene expression in human cells using humanized protein components and demonstrates their use in inducible gene expression in T-cells.