Cell BiologyAlzheimer s & DementiaPeer-reviewed
Tracking tau and cellular responses in human iPSC-microglia from uptake to seedable secretion in extracellular vesicles
Maria Kreger Karabova, Anna del Ser‐Badia, Anne Hedegaard…·Sally A. Cowley
This study shows human iPSC-derived microglia uptake and process tau fibrils, leading to secretion in extracellular vesicles that can seed tau aggregation in neurons.
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