Ning Zhang

Targeted protein degradation of the CPSF complex by benzoxaboroles through sumoylation

This study identifies CPSF3 as a target of benzoxaboroles in trypanosomatids, showing that BoBs induce sumoylation-dependent degradation of CPSF complex members, leading to reduced mRNA levels.

PSMC2 and CXCL8-Modulated Four Critical Gene Biomarkers and Druggable and Vaccinable Targets for Colorectal Cancer

The paper identifies four critical differentially expressed genes in colorectal cancer using transcriptomic data from multiple cohorts and validates their predictive power and potential as druggable/vaccinable targets.

Circular RNA's competing endogenous gene pair as motif in serous ovarian cancer

The paper identifies circular RNA competing endogenous gene pairs (cceGPs) as predictive indicators for serous ovarian cancer using a novel method and validates their predictive capacity in independent cohorts.