Author

Ning Zhang

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Pharmacology & Toxicology· 2 Bioinformatics· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Ao WangiD· 2 shared Gaojian Chen· 2 shared Kingsley Leung· 2 shared Liang CheniD· 2 shared Weihai Chen· 2 shared Yongkang Long· 2 shared Zhangzhan Xu· 2 shared Zhiming Liang· 2 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersPharmacology & Toxicology

Ao WangORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Discriminating rare disease cases from their controls based on observed and excluded phenotypes

Yanting Guo, Yang Yao, Yiyao Zhang, Guangyou Duan, Ning Zhang, Shan Gao

This study uses machine learning to distinguish rare disease cases from controls using observed and excluded phenotypes, finding that Random Forest performs best and both specificity and occurrence count are important for feature selection.

bioRxiv · Sep 21, 2026 · PreprintBioinformatics

AlfaDAX-Derived ActRIIA/B Antibody with Semaglutide Enhances Fat Loss and Improves Weight-Loss Quality in DIO Mice

Ning Zhang, Yongkang Long, Zhangzhan Xu, Gaojian Chen, Ao Wang, Weihai Chen, Zhongwei Chen, Zhiming Liang, Kingsley Leung, Liang Chen

This study develops an anti-ActRIIA/B antibody, AB130-165, which, when combined with semaglutide, leads to greater weight loss and better preservation of lean mass in diet-induced obese mice compared to monotherapy or bimagrumab combinations.

bioRxiv · Jul 13, 2026 · PreprintPharmacology & Toxicology

Mechanistic dissection of Candidatus Liberibacter Triggered Chronic Immune Disease

Xiaoen Huang, Wenxiu Ma, Wenting Wang, Yu Feng, Jinyun Li, Tirtha Lamichhane, yuanchun wang, Jin Xu, Sheo Shankar Pandey, Diann Achor, Javier L. Dalmendray, Zhuyuan Hu, Camila de Araújo Lima Ribeiro, Ning Zhang, Madhurababu Kunta, , Nian Wang

This study shows that Candidatus Liberibacter triggers immune responses in citrus plants, leading to cell death and disease, and identifies genetic targets to mitigate these effects.

Cell Host & Microbe · May 11, 2026Peer-reviewedPlant Biology

Generation of High-Affinity Anti-GIPR Antagonist Antibodies with Sustained and Non-rebound Weight Loss in DIO Mice by AlfaBodY

Yongkang Long, Zhangzhan Xu, Ning Zhang, Gaojian Chen, Weihai Chen, Zhongwei Chen, Ao Wang, Zhiming Liang, Yingya Wang, Yi Zeng, Kingsley Leung, Liang Chen

This study uses AI to design high-affinity anti-GIPR antibodies that induce sustained weight loss in obese mice without rebound.

bioRxiv · Apr 24, 2026 · PreprintPharmacology & Toxicology