This study validates a single oocyte biopsy method in bovine by comparing it to whole oocytes, showing high correlation in gene expression despite minor differences.

bioRxiv · Apr 24, 2023 · PreprintBioinformatics

Retrospective model utilizing biopsies, granulosa cells, and polar body to predict oocyte competence in bovine

Dewison Ricardo Ambrizi, Tiago Henrique Camara De, Ricardo Perecin Nociti, João Vitor Puttini Paixão, Marcos Roberto Chiaratti, Juliano Rodrigues Sangalli, Juliano Coelho da Silveira, Felipe Perecin, E. C. Mattos, José Bento Sterman Ferraz, Jacinthe Therrien, Lawrence Charles Smith, Flávio Vieira Meirelles

This paper predicts oocyte competence in bovine using RNA-seq and WGBS from biopsies, cumulus cells, granulosa cells, and polar bodies, identifying transcriptional and epigenetic differences between cleaved but arrested and blastocyst-stage embryos.

bioRxiv · Apr 23, 2023 · PreprintGenomics

Genomic epidemiology reveals the impact of national and international restrictions measures on the SARS-CoV-2 epidemic in Brazil

Marta Giovanetti, Svetoslav Nanev Slavov, Vagner Fonseca, Eduan Wilkinson, Houriiyah Tegally, José Salvatore Leister Patané, Vincent Louis Viala, James Emmanuel San, Evandra Strazza Rodrigues, Elaine Vieira Santos, Flávia Figueira Aburjaile, Joilson Xavier, Hegger Machado Fritsch, Talita Adelino, Felicidade Mota Pereira, , Maria Carolina Elias

The paper uses genomic data to analyze how national and international restrictions affected SARS-CoV-2 transmission in Brazil and Paraguay, showing the spread of variants and the role of importation.

Nature Microbiology · Aug 18, 2022Peer-reviewedGenetic & Genomic Medicine