John J Marshall

This study investigates how movement refinement and cholinergic signaling influence skilled reaching in mice, finding that ACh levels and outcome-dependent adjustments play roles in updating movement execution.

This study shows that Fmr1 knockout mice exhibit exaggerated NMDA receptor-mediated metaplasticity due to SK channel dysregulation, affecting hippocampal LTP and potentially contributing to learning impairments in Fragile X syndrome.

This study shows that mGluR5 modulates co-activity of striatal direct pathway neurons and motor output through synaptic plasticity.

The paper evaluates peptidomimetic inhibitors targeting TrkB/PSD-95 signaling in an Angelman Syndrome mouse model, showing improved seizure outcomes and cognition but not motor function.