Author

Nai-Hsing Yeh

Northwestern UniversityORCID 0000-0002-7733-7475Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:electronic health records· 2 Research Focus:spatial domain detection· 2

Frequent Co-Authors

Anis ContractoriD· 4 shared Jian XuiD· 2 shared John J MarshalliD· 2 shared John N. Armstrong· 2 shared Jones G. ParkeriD· 2 shared Seongsik YuniD· 2 shared Toshihiro NomuraiD· 2 shared Anika P. WileniD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersNeuroscience

Anis ContractorORCID

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4 papers

Recent·Most cited

Movement refinement and cholinergic regulation of outcome-dependent updating during skilled reaching.

Nai-Hsing Yeh, Lily Prokop, John J Marshall, Anis Contractor

This study investigates how movement refinement and cholinergic signaling influence skilled reaching in mice, finding that ACh levels and outcome-dependent adjustments play roles in updating movement execution.

bioRxiv · Oct 30, 2026 · PreprintNeuroscience

Synaptic mechanisms modulate the spatiotemporal dynamics of striatal direct pathway neurons and motor output

John J Marshall, Jian Xu, Nai-Hsing Yeh, Seongsik Yun, Toshihiro Nomura, John N. Armstrong, Jones G. Parker, Anis Contractor

This study shows that mGluR5 modulates co-activity of striatal direct pathway neurons and motor output through synaptic plasticity.

eLife · Jan 27, 2026Peer-reviewedNeuroscience

A pathogenic missense mutation in kainate receptors elevates dendritic excitability and synaptic integration through dysregulation of SK channels

Toshihiro Nomura, Sakiko Taniguchi, Yizhi Wang, Nai-Hsing Yeh, Anika P. Wilen, Charlotte Castillon, Kendall M. Foote, Jian Xu, John N. Armstrong, Jeffrey N. Savas, Geoffrey T. Swanson, Anis Contractor

This study investigates a missense mutation in the GRIK2 gene, showing it disrupts SK channel function, leading to increased dendritic excitability and synaptic integration in hippocampal neurons.

Journal of Neuroscience · Oct 6, 2023Peer-reviewedNeuroscience

Modulating D1 rather than D2 receptor-expressing spiny-projection neurons corresponds to optimal antipsychotic effect

Seongsik Yun, Ben Yang, Justin D. Anair, Madison M. Martin, Stefan W. Fleps, Arin Pamukcu, Nai-Hsing Yeh, Anis Contractor, Ann Kennedy, Jones G. Parker

The paper investigates the neural mechanisms of antipsychotic drugs by comparing their effects on D1- and D2-receptor-expressing spiny-projection neurons in mice, finding that modulating D1-SPNs correlates with therapeutic efficacy.

Nature Neuroscience · Jul 13, 2023Peer-reviewedNeuroscience