Tomoya S. Kitajima

This study uses ex vivo live imaging to observe oocyte formation dynamics in mice, revealing blebbing activity during mitosis-to-meiosis transition and no organelle transfer between germ cells.

This study shows that Kif11 haploinsufficiency in mouse oocytes leads to impaired spindle bipolarization and spatially differential chromosome biorientation.

The paper shows that kinetochores promote timely spindle bipolarization in mouse oocytes to reduce microtubule attachment errors and aneuploidy risk.

This study uses single-cell RNA sequencing to analyze WNT signaling's role in granulosa cell-oocyte interactions during primordial follicle activation, revealing transcriptomic changes and their impact on fertility.

This study demonstrates that tethering NDC80-NUF2 to microparticles enables biorientation in mouse oocytes without requiring other kinetochore components.

This study shows that reducing ooplasmic volume in oocytes improves meiotic accuracy and embryo development, enabling offspring production from azoospermic mice with spermatocyte arrest.