Author

Hongbing Yu

BC Children's Hospital Research InstituteORCID 0000-0002-6527-9677Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Bruce Andrew VallanceiD· 2 shared Caixia MaiD· 2 shared Abraham Stijn MeijnikmaniD· 1 shared Arnold W. J. M. van de LaariD· 1 shared Bert‐Jan H. van den BorniD· 1 shared C. Bruce VerchereiD· 1 shared Clara BelzeriD· 1 shared Daniël H. van RaalteiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Bruce Andrew VallanceORCID

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2 papers

Recent·Most cited

The growth and pathogenesis of Citrobacter rodentium is compromised by disrupted mucin sugar pathways that accumulate N-acetylglucosamine 6-phosphate

Zhiquan Clarence Huang, Matthias Ahmad Mslati, Caixia Ma, Hyungjun Yang, Qiaochu Liang, Shauna M. Crowley, Roger Dyer, Irene Oi‐Lin Ng, Hongbing Yu, Bruce Andrew Vallance

This paper shows that disrupting mucin sugar pathways in Citrobacter rodentium leads to accumulation of N-acetylglucosamine 6-phosphate, impairing bacterial growth and pathogenesis in mice.

bioRxiv · Aug 18, 2025 · PreprintMicrobiology

Gut-derived bacterial flagellin induces beta-cell inflammation and dysfunction

Torsten P. M. Scheithauer, Hilde Herrema, Hongbing Yu, Guido J. Bakker, Maaike Winkelmeijer, Galina Soukhatcheva, Derek L. Dai, Caixia Ma, Stefan R. Havik, Manon Balvers, Mark Davids, Abraham Stijn Meijnikman, Ömrüm Aydin, Bert‐Jan H. van den Born, Marc G. Besselink, , Daniël H. van Raalte

This study shows that gut-derived bacterial flagellin contributes to beta-cell inflammation and dysfunction in type 2 diabetes.

Gut Microbes · Aug 19, 2022Peer-reviewedMolecular Biology