Author

Ruman Rahman

University of NottinghamORCID 0000-0002-6541-9983Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Approach:microscopy & imaging analysis· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Stuart J. Smith· 2 shared A. Philip McMahon· 1 shared Adam Mark BlanchardiD· 1 shared Aditi Mandar Atmasidha· 1 shared Alan R. PrescottiD· 1 shared Alessandra Fistrovich· 1 shared Alina PandeleiD· 1 shared Amy Dunne MilleriD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

Stuart J. Smith

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

FluoVolt Staining Induces Photodamage During Live-Cell Voltage Imaging

Evren M. Akyuz, Manuela Mitroi, Fleur E Groualle, Foteini Patera, Ruman Rahman, Stuart J. Smith, Ian Spendlove, Judith M. Ramage, Hester Franks, Andrew Mark Jackson, Adam Mark Blanchard, Anna A. Malecka, Frankie James Rawson

This study shows FluoVolt staining and excitation cause photodamage and cell perturbation in live-cell voltage imaging, with recommendations to reduce dye concentration and loading time.

bioRxiv · Jun 11, 2026 · PreprintBiophysics

Spatially confined niches support hypoxia-associated transcriptional plasticity contributing to malignant progression in IDH-mutant gliomas

Depro Das, Alina Pandele, Vatsal D. Jariwala, Nishitha S Ghariwala, Aso O. Mohammed, Tonmoy Das, Christopher Krolla, Saif Mukramoon Arosh, Naiem Hossain, Mohammad Al Shhab, Md. Ismail Hosen, Stuart J. Smith, Juergen Grauvogel, Ioannis Vasilikos, Roland Roelz, , Sajib Chakraborty

This study identifies hypoxia-associated transcriptional plasticity in IDH-mutant gliomas, showing microglia-driven quiescent-to-activated transitions that drive malignant progression.

bioRxiv · Jun 3, 2026 · PreprintCancer Biology

Single-Cell Metabolic Profiling in a Glioblastoma Co-culture Model Using AP-MALDI-based Mass Spectrometry Imaging

Une Kontrimaite, Kei F. Carver Wong, Sandra Martínez‐Jarquín, Phoebe McCrorie, Ruman Rahman, Dong‐Hyun Kim

This paper introduces a single-cell mass spectrometry imaging platform to profile metabolites in glioblastoma co-cultures, revealing cell-type-specific metabolic signatures and interactions.

Analytical Chemistry · Apr 7, 2026Peer-reviewedCancer Biology

Dyr726, a brain-penetrant inhibitor of PI3Kα, Type III receptor tyrosine kinases, and WNT signalling

Vasudha Tandon, Alessandra Fistrovich, Joaquina Nogales, Febe Ferro, Samantha Rokey, Carly R. Cabel, Amy Dunne Miller, Mary Yagel, Christina Duncan, Aditi Mandar Atmasidha, Ira Sharma, Gerrit Wilms, Karin Williams, Richard J. R. Elliott, Timothy Chavez, , Sourav Banerjee

This paper designs and evaluates Dyr726, a brain-penetrant multi-kinase inhibitor that targets PI3Kα, receptor tyrosine kinases, and WNT signaling, showing efficacy in preclinical cancer models.

bioRxiv · Mar 26, 2025 · PreprintCancer Biology