Esther Klingler

This study compares prenatal cortical development in two rodents, showing that major developmental milestones occur prenatally in Acomys, challenging the view that postnatal experience is essential for early brain maturation.

The paper identifies JUNB as a gene driving species-specific cortical features by comparing gene expression in mouse, human, and human cortical organoids.

The paper investigates how environmental factors influence neocortical neuron fate and diversity through in vivo and in vitro experiments, showing population-specific responses and the importance of extracellular context.

This study shows that heterotopic neurons in EmlJ knockout mice retain functional properties similar to neocortical neurons despite their abnormal location.

The paper identifies developmental molecular programs that control the emergence and area-specific distribution of two subtypes of cortical motor projection neurons.

This study identifies that the transcriptional identities of intracortically-projecting neurons primarily reflect their input-output connectivities rather than their birth dates or laminar positions.

The paper develops ConnectID, a method linking connectome and transcriptome in single neurons, identifying transcriptional modules associated with axonal projections to specific cortical and subcortical targets.