Veronica M. Pravatà

This study develops human cerebral assembloids to model glioblastoma interactions with glial cells, revealing extracellular vesicles' role in peritumoral niche formation.

The paper identifies JUNB as a gene driving species-specific cortical features by comparing gene expression in mouse, human, and human cortical organoids.

This paper develops a 3D cortical brain tissue model with mature microglia that recapitulates Alzheimer's disease hallmarks and enables study of microglia phenotypes.

The paper identifies a human-specific mutation in DCHS1 that alters glycosylation and affects forebrain proportions by changing striatal and neocortical progenitor ratios.

This study uses cerebral organoids to show that EPM1 mutations disrupt neural cell fate specification through intrinsic and extrinsic mechanisms involving EVs and SHH signaling.

This study investigates neuronal hyperactivity in human cerebral organoids derived from individuals with grey matter heterotopia, identifying functional and structural changes linked to the condition.

The paper shows that an OGT variant causes reduced pluripotent stem cell self-renewal and lower stem cell marker levels in mouse embryonic stem cells.